Monday, February 25, 2013

Training Needs in Response to Big Data to Knowledge (BD2K) Initiative

Additional Information:
http://grants.nih.gov/grants/guide/notice-files/NOT-HG-13-003.html

Purpose

The National Institutes of Health is launching Big Data to Knowledge (BD2K), an initiative to address how best to manage and utilize the large amounts of biomedical data that new technologies can generate (http://www.nih.gov/news/health/dec2012/od-07.htm). This initiative resulted from a set of recommendations from the Data and Informatics Working Group to the Advisory Committee to the Director, NIH (Data and Informatics Working Group). As part of the its response to the recommendations, NIH has established a working group to develop plans to implement new programs to increase training in this area, and this working group intends to convene a workshop to discuss training and education needs in how to manage and utilize large complex data sets. Prior to the workshop, NIH wishes to collect information and relevant materials that will help inform the discussions of the workshop participants.

Background

The era of ‘Big Data’ has arrived for biomedical research, bringing with it immense challenges as well as spectacular opportunities. In this context, ‘Big Data’ is meant to reflect the challenges facing biomedical researchers of all stripes in accessing, organizing, analyzing, and integrating datasets that are increasingly larger, more complex, and more numerous. These data are also of diverse types that must be integrated, including imaging, phenotypic, molecular, exposure, health, and many other types of biomedical, behavioral and clinical data. While used here for convenience, the phrase ‘Big Data’ is intended to be shorthand for the reality that biomedical research has become a data-intensive enterprise.

Advances in biomedical sciences using Big Data will require more scientists with appropriate expertise and skills, some of whom will be critical members of interdisciplinary teams. NIH is interested in increasing funding for long- and short-term training at all professional levels, in areas essential for accessing, organizing, analyzing, and integrating biomedical Big Data (e.g., computational biology, biostatistics, bioinformatics, the quantitative sciences, and related areas).

Information Requested

The workshop will address the long- and short-term training needs of professionals and trainees with the purposes of increasing the number of: (1) informaticians and computational and quantitative scientists who wish to apply their skills and knowledge in the biomedical, behavioral and clinical sciences and (2) biomedical, behavioral, and clinical scientists who have the requisite knowledge and skills to effectively access, organize, analyze, and integrate large and complex data sets. To aid in planning this workshop, responses are being sought from the extramural community on the following:

Characteristics and Contents of Plans for Cross-Training Biomedical, Behavioral, Clinical, Computational, and Quantitative Scientists and Informaticians at All Career Levels:

  • Doctoral and postdoctoral training programs that will be needed to expand the capabilities of the targeted groups to use Big Data, with special attention to the training and mentoring environments.
  • Short-term training, including course content that will be needed to cross-train the targeted groups and undergraduates.
  • New curriculum and other training materials that will be needed to cross-train the targeted groups and undergraduates.

Monday, February 4, 2013

Understanding Type 2 Diabetes in Youth: Lessons from the TODAY Study

Dr. Neil H. White, M.D., C.D.E. did a talk on Monday January 28, 2013, entitled "Understanding Type 2 Diabetes in Youth: Lessons from the TODAY Study." If you'd like a copy of his power point presentation please click here: http://cdtr.wustl.edu/images/attachments/todayforcdtr012813.pdf.

Dr. White is a Professor of Pediatrics and Director of the Pediatric Clinical Research Unit. His research interests have included active participation as a co-investigator and co-principal investigator of the Diabetes Control and Complications Trial (DCCT) both at Washington University and the University of Michigan. He is currently the principal investigator at Washington University for the DCCT/EDIC study. Dr. White has had an ongoing interest in the methods of intensive therapy in Type 1 and the risk of hypoglycemia as part of the therapy. He oversees the Diabetes Prevention Program (DPP) and the DPP Outcomes STUDY (DPPOS), multiple trials of psychosocial intervention in diabetic teenagers, the STOPP-T2D/TODAY study, related to treatment and prevention of Type 2 diabetes in youth TRIGR and is the Chairman of the Steering Committee and local PI for the Diabetes in Children Research Network (DirecNet).  In addition, Dr. White is the Associate Director of the Center for Diabetes Translation Research.

His talk coincided with a major news release entitled "Diabetic Kids' New Regimen: Push for Early Insulin Shots for Many Children Highlights Growing Cases of Type 2 Diabetes" found in the Wall Street Journal. For those interested in this article, please visit the following website: http://online.wsj.com/article/SB10001424127887323644904578267834224648420.html.

For a related article entitled "Psychosocial Resources and Barriers to Self-management in African American Adolescents with Type 2 Diabetes," please visit the following website: http://bit.ly/XFDNnT.